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An aphrodisiac is a substance that increases sexual desire.

It is featured in the first Bible Black game as a hypodermic needle with a green fluid that is injected into the genital area. It is also seen as a small capsule inserted orally or vaginally that breaks open inside the body. In the Bible Black: La Noche de Walpurgis anime series, the aphrodisiacs appear as small green pills that are taken orally.

Overusing the drug can result in extreme intoxication or even death.

In Saeki's apartment, the evil Academy nurse Reika Kitami force feeds several aphrodisiac pills to student Kurumi Imari in order to abuse and torture her. Her follower Kaori Saeki hands Kitami the pills from a small white bottle, but it is likely that they belong to Kitami originally. Imari quickly succumbs to the drugs, despite desperately trying to hold her composure. Her body is pleasured by Kitami's lackeys Jun and Maki, and she later has anal sex with her friend Taki Minase, several of Kitami's male followers and Kitami herself, her mind completed absorbed in pleasure from the chemicals.

Kitami later captures art teacher Hiroko Takashiro and gives her an overdose of pills, causing the intoxication to linger for several hours after she is released from her captivity. In an attempt to shake off the effects, the professor pleads with her student Minase to relieve her, and they passionately have sex multiple times at his house.
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